Predicting hepatotoxicity using cell based assays
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United States of America Patent
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Jun 26, 2007
Grant Date -
Jan 20, 2005
app pub date -
Jul 18, 2003
filing date -
Jul 18, 2003
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Expired
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Abstract
Cell based assays are used to assess the hepatotoxicity of a stimulus. Imaging technologies are used to analyze the effects of a stimulus on hepatocytes. Image analysis may characterize the stimulus on the basis of whether it is hepatotoxic, and if so what type of pathology is exhibited; e.g., apoptosis, necrosis, cholestasis, and/or steatosis.
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