Compositions and methods for modulating NH2-terminal Jun Kinase activity
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United States of America Patent
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Jun 19, 2007
Grant Date -
Nov 24, 2005
app pub date -
Apr 24, 2002
filing date -
Apr 24, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Disclosed herein are compositions and methods used to modulate a NH.sub.2-terminal Jun Kinase activity. These compositions and methods can be employed to regulate metabolic disorders associated with, for example, insulin such as diabetes. The reduction in NH.sub.2-terminal Jun Kinase activity can lead to the reduction in weight and improve insulin sensitivity.
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