Multiplex analysis for high throughput discrimination of GPCR agonists and antagonists

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United States of America Patent

PATENT NO 7232659
SERIAL NO

10771853

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Abstract

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The present invention relates generally to molecular assemblies, more particularly to an assay for the detection of G-protein coupled receptor (GPCR) molecular assemblies and bead-based detection of ligand-GPCR complexes and to methods for identifying compounds as agonists, partial agonists or antagonists of the binding of G-protein coupled receptors to G-protein and for use of these compounds in the treatment of conditions or disease states in a mammalian subject or patient, including humans, where G-protein coupled receptor binding to G-protein is implicated.

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Patent Owner(s)

Patent OwnerAddress
SCIENCE & TECHNOLOGY CORPORATION @ UNM801 UNIVERSITY BLVD SE SUITE 101 ALBUQUERQUE NM 87106

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Biggs, Sean Albuquerque, NM 1 0
Cimino, Daniel Tijeras, NM 2 6
Prossnitz, Eric R Albuquerque, NM 14 48
Simons, Peter Albuquerque, NM 3 27
Sklar, Larry A Albuquerque, NM 58 580
Waller, Anna Albuquerque, NM 3 3

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