Assays and peptide substrate for determining aggrecan degrading metallo protease activity
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United States of America Patent
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May 29, 2007
Grant Date -
Nov 14, 2002
app pub date -
Oct 12, 2001
filing date -
Jul 25, 1997
priority date (Note) -
Expired
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Abstract
This invention is directed to assays to determine the presence or absence of proteins that exhibit aggrecanase or ADMP activity. This invention also relates to peptides that acts as a substrates for ADMPs, their use in various assays to determine the presence or absence of ADMP activity, and their use as inhibitors of ADMP activity.
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