Diagnosis of the presence of cochlear hydrops using observed auditory brainstem responses

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United States of America Patent

PATENT NO 7223246
APP PUB NO 20050273018A1
SERIAL NO

10863559

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Abstract

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A procedure for diagnosing cochlear hydrops is based, in part, on an analysis of the patient's auditory brainstem response (ABR) to stimuli. The patient's ABR to a broadband click stimulus is recorded. A plurality of masked ABR's are also recorded, wherein the stimulus is masked by high-pass noise with a plurality of high-pass cut-off frequencies. The latency difference between the wave V component in the unmasked click alone response and the undermasked wave V component of a low cut-off frequency high-pass response is then calculated. If an undermasked component is not present, the normal wave V component is used. The measured latency difference is combined with another measure, such as the wave V amplitude ratio. A distribution of the combined measure is then plotted for the population and a threshold established for diagnosing cochlear hydrops. Alternatively, the joint distribution of the individual measures may be used in situations where the individual measures are known to be independent.

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Patent Owner(s)

Patent OwnerAddress
HOUSE EAR INSTITUTE2100 WEST THIRD STREET SUITE 111 LOS ANGELES CA 90057

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Don, Manuel Anaheim, CA 5 84

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