3-phenylpropionic acid derivatives

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United States of America Patent

PATENT NO 7220766
APP PUB NO 20060160870A1
SERIAL NO

11332708

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Abstract

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The invention relates to new compounds, 3-phenylpropionic acid derivatives of formula (I) wherein W represents COOH group or its bioisosters, or --COO--C.sub.1 C.sub.4-alkyl group; Y represents NH, N--C.sub.1 C.sub.10-alkyl, O, or S; X represents O, S, NH, N--C.sub.1 C.sub.10-alkyl, N-aryl, NSO.sub.2--C.sub.1 C.sub.10-alkyl, N--SO.sub.2-aryl, or N--SO.sub.2-heteroaryl; R.sub.1 to R.sub.8 each independently represents hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof. The compounds are the ligands of PPAR-gamma receptor and are useful as medicaments ##STR00001##

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Patent Owner(s)

Patent OwnerAddress
ADAMED SP Z O O05-152 CZOSNÓW K/WARSZAWY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kludkiewicz, Dominik Daniel Warsaw, PL 3 1
Kowalczyk, Piotr Warsaw, PL 6 11
Kurowski, Krzysztof Siedlce, PL 7 15
Majka, Zbigniew Lubzina, PL 6 13
Matusiewicz, Katarzyna Joanna Lwowek Slaski, PL 5 13
Rusin, Katarzyna Ewa Warsaw, PL 5 13
Sawicki, Andrzej Wojciech Jozefow, PL 3 8
Stawinski, Tomasz Wiazowna, PL 7 14
Sulikowski, Daniel Gubin, PL 7 13

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