Isoquinoline compound and pharmaceutical use thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7220759
APP PUB NO 20040248931A1
SERIAL NO

10836377

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to an isoquinoline compound represented by the following formula (I), an optically active form thereof, a pharmaceutically acceptable salt thereof, a water adduct thereof, a hydrate thereof and a solvate thereof, as well as an agent for the prophylaxis and/or treatment of a disease caused by hyperreactivity of poly(ADP-ribose)polymerase, containing the compound, and a poly(ADP-ribose)polymerase inhibitor containing the compound. In addition, this compound is useful as an agent for the prophylaxis and/or treatment of cerebral infarction, particularly as an agent for the prophylaxis and/or treatment of acute cerebral infarction. Furthermore, this compound is useful as a prophylactic and/or therapeutic agent that improves neurological symptoms associated with cerebral infarction, particularly acute cerebral infarction. ##STR00001## wherein the symbols are the same as defined in the description.

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Patent Owner(s)

Patent OwnerAddress
MITSUBISHI PHARMA CORPORATIONCHUO-KU OSAKA-SHI

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Egi, Yasuhiro Tokyo, JP 7 132
Fujio, Masakazu Tokyo, JP 27 355
Inoue, Shinya Tokyo, JP 36 343
Matsumoto, Toshifumi Tokyo, JP 11 69
Satoh, Hiroyuki Tokyo, JP 115 1568

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