Identification of the gene causing the mouse scurfy phenotype and its human ortholog
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United States of America Patent
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May 22, 2007
Grant Date -
Jul 28, 2005
app pub date -
Nov 15, 2004
filing date -
Aug 11, 1998
priority date (Note) -
Expired
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Abstract
Isolated nucleic acid molecules are provided which encode Fkh.sup.sf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Utilizing assays based upon the nucleic acid sequences disclosed herein (as well as mutant forms thereof), numerous molecules may be identified which modulate the immune system.
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