Compounds and methods for treatment of thrombosis
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United States of America Patent
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May 15, 2007
Grant Date -
Jun 30, 2005
app pub date -
Apr 2, 2004
filing date -
Apr 2, 2003
priority date (Note) -
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Abstract
The present invention provides compounds that inhibit Factor XIa and methods of preventing or treating undesired thrombosis by administering a compound of the invention to a mammal. The invention also provides three-dimensional structures of Factor XIa and methods for designing or selecting additional Factor XIa inhibitors using these structures.
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