Test strip for determining concentration of triglycerides
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United States of America Patent
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May 8, 2007
Grant Date -
Sep 11, 2003
app pub date -
Dec 30, 2002
filing date -
Dec 28, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A dry-phase triglycerides test strip that can be stored at room or elevated temperatures for several months without significant degradation in its effectiveness. The test strip includes a test membrane which receives plasma and forms a colored response in proportion to concentration of triglycerides in the plasma. The test membrane is impregnated with an aqueous solution containing lipoprotein lipase (LPL) and 4-aminoantipyrine (4AAP). The inventors have found that by reducing the pH of the impregnating solution to less than that of the recommended pH range for one of the key components (viz., less than pH 6.0), overall stability of the test strips was dramatically improved. The improvement in storage capability of these triglycerides test strips represents not just a difference in degree, but a difference in kind.
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