Methods of co-expressing umami taste receptors and chimeric G.alpha..sub.15 variants
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United States of America Patent
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Apr 24, 2007
Grant Date -
Nov 27, 2003
app pub date -
Dec 13, 2002
filing date -
Dec 14, 2001
priority date (Note) -
Expired
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Abstract
The invention provides a series of chimeric G.sub..alpha.15 protein variants that couple to certain GPCRs more efficiently than the native G.alpha..sub.15 protein. These chimeric G.sub..alpha.15 protein variants can be used to discover and analyze modulators of GPCRs (especially those that mediate taste perception).
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