Methods for treating disease and forming a supplemented fibrin matrix

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United States of America Patent

PATENT NO 7208179
SERIAL NO

08485898

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Abstract

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This invention provides supplemented and unsupplemented tissue sealants as well as methods for their production and use thereof. Disclosed are tissue sealants supplemented with at least one oligonucleotide. The composition may be further supplemented with, for example, one or more analgesics, antimicrobial compositions, anticoagulants, antiproliferatives, anti-inflammatory compounds, cytokines, cytotoxins, drugs, growth factors, interferons, hormones, lipids, demineralized bone or bone morphogenetic proteins, cartilage inducing factors, oligonucleotides polymers, polysaccharides, polypeptides, protease inhibitors, vasoconstrictors or vasodilators, vitamins, minerals, stabilizers and the like.

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Patent Owner(s)

Patent OwnerAddress
THE GOVERNMENT OF THE USA AS REPRESENTED BY THE SECRETARY OF THE ARMY ON BEHALF OF USAMRMC504 SCOTT STREET ATTN MCMR-JA FORT DETRICK MD 21702-5012

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Drohan, William N Springfield, VA 81 1815
Hollinger, Jeffrey O Gibsonia, PA 17 505
MacPhee, Martin James Gaithersburg, MD 5 931

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