Method for producing temperature-sensitive morbillivirus
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United States of America Patent
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Apr 24, 2007
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N/A
app pub date -
Oct 18, 2000
filing date -
Feb 10, 2000
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Abstract
It was found that a mutation of an amino acid at a specific position in the P protein of a morbillivirus gives a temperature-sensitivity character to a virus. By introducing this mutation, a virus to which a temperature-sensitivity character has been introduced can be produced. According to this invention, attenuated viruses useful in the preparation of vaccines can be easily produced.
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