Cyclic peptides, method for preparing and use as angiogenesis inhibitors or activator
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United States of America Patent
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Apr 3, 2007
Grant Date -
May 13, 2004
app pub date -
Oct 2, 2001
filing date -
Oct 4, 2000
priority date (Note) -
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Abstract
The invention relates to cyclopeptides, the method of their preparation and their utilization as inhibitors or activators of angiogenesis.These cyclopeptides comprise the following peptide sequence: -Arg-Ile-Lys-Pro-His-Gln-Gly-They can be used in systems for inhibition of angiogenesis that comprises a support (1), to which the cyclopeptide is affixed by means of an organic spacer arm (3) that may be provided with a moiety (4) capable of being spliced by an enzyme system.
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