Method of producing teicoplanin
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United States of America Patent
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Mar 20, 2007
Grant Date -
Nov 3, 2005
app pub date -
Apr 15, 2005
filing date -
Apr 16, 2004
priority date (Note) -
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Abstract
Disclosed is a method of producing teicoplanin. The method includes purifying teicoplanin from a culture broth, obtained by culturing microorganisms capable of producing teicoplanin by a porous adsorption resin under selective elution conditions and recovering highly pure teicoplanin using activated carbon and/or ultrafiltration. In this regard, the method can further include ultrafiltration as pre-treatment before the culture broth is adsorbed into the porous adsorption resin so as to increase the purity of teicoplanin.
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