FO-6979 substances and process for producing the same

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7192742
APP PUB NO 20030195146A1
SERIAL NO

10343990

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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(Beauveria) sp. FO-6979 (FERM BP-6681), which belongs to the genus Beauveria and is capable of producing FO-6979-M0, -M1, -M2, -M3 and -M4 substances, is cultured in a medium to thereby accumulate the FO-6979-M0, -M1, -M2, -M3 and -M4 substances in the liquid culture medium. Then the FO-6979-M0, -M1, -M2, -M3 and -M4 substances are collected from the culture medium. The substances thus obtained are less toxic, specifically inhibit acyl-Coenzyme A: cholesterol acyltransferase, and inhibit the formation of oil droplets in macrophages. Owing to these characteristics, the above substances are useful in preventing and treating human diseases caused by cholesterol accumulation.

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Patent Owner(s)

Patent OwnerAddress
GAKKOU HOUJIN KITASATO GAKUENTOKYO 108-8641

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Omura, Satoshi Tokyo, JP 102 462
Tomoda, Hiroshi Tokyo, JP 44 171

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