Methods and compositions as protein kinase inhibitors
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United States of America Patent
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Mar 13, 2007
Grant Date -
Aug 4, 2005
app pub date -
Sep 30, 2004
filing date -
Sep 30, 2003
priority date (Note) -
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Abstract
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, EGF-R, c-erbB2 kinase (HER-2), CHK2, FGFR3, p70S6K, PKC, PDGF-R, p38, TGF.beta., KDR, c-Kit, b-RAF, c-RAF, FLT1 and/or FLT4 kinases.
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