2, 3-benzodiazepine derivatives and pharmaceutical compositions containing the same as the active ingredient
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United States of America Patent
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Mar 13, 2007
Grant Date -
May 13, 2004
app pub date -
Dec 19, 2001
filing date -
Dec 21, 2000
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Abstract
The invention refers to novel 2,3-benzodiazepine derivatives of formula (I) and pharmaceutical compositions containing the same as the active ingredient. The novel compounds antipasmodic, muscle relaxant and neuroprotective activities. In formula I; X represents a hydrogen atom, a chloro atom or a methoxy group; Y stands for a hydrogen atom or a halo atom; Z means a methyl group or a chloro atom; R is a C.sub.1-4 alkyl group or a group of the formula --NR.sup.1R.sub.2, wherein R.sup.1 and R.sup.2 represent, independently, a hydrogen atom, a C.sub.1-4 alkyl group, a C.sub.1-4 alkoxy group or a C.sup.3-6 cycloalkyl group. ##STR00001##
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