Polypeptide conjugates with extended circulating half-lives

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United States of America Patent

PATENT NO 7186797
APP PUB NO 20040254119A1
SERIAL NO

10487025

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to compounds and methods for synthesizing compounds wherein the compounds exhibit extended circulating half-life in the blood. The increase in circulating half-life is achieved by conjugating polypeptides to binding groups that exhibit high affinity for human serum albumin.

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Patent Owner(s)

Patent OwnerAddress
EPIX PHARMACEUTICALS INC161 FIRST STREET CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dumas, Stephane Cambridge, MA 16 130
Kolodziej, Andrew Winchester, MA 23 182
McMurry, Thomas J Winchester, MA 32 488
West, Theodore R Boston, MA 1 25

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