Treatment of arthritis with arsenoxide compounds
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United States of America Patent
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Mar 6, 2007
Grant Date -
Jul 15, 2004
app pub date -
Mar 19, 2002
filing date -
Mar 19, 2001
priority date (Note) -
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Abstract
The present invention provides a method of treatment and/or prophylaxis of arthritis in a vertebrate comprising administering to said vertebrate in need of said treatment and/or prophylaxis a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof, optionally together with a pharmaceutically acceptable carrier, diluent or excipient, wherein said compound of formula (I) is defined as: A--(L--Y).sub.p, wherein: A comprises at least one substantially cell-membrane impermeable pendant group; L comprises any suitable linker and/or spacer group; Y comprises at least one arsenoxide or arsenoxide equivalent; p is an integer from 1 to 10; and the sum total of carbon atoms in A and L together, is greater than 6.
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