Composition and method for treating graft-versus-host disease
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United States of America Patent
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Feb 6, 2007
Grant Date -
Feb 2, 2006
app pub date -
Aug 18, 2005
filing date -
Oct 12, 2001
priority date (Note) -
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Abstract
Compositions and methods are provided for prevention and clinical treatment of various forms of graft-versus-host disease (GVHD) by using inhibitors of adenosine deaminase (ADA). In particular, various formulations and dosing regimens of ADA inhibitors such as pentostatin are provided for the treatment of all forms of GVHD, especially steroid-refractory acute and chronic GVHD.
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