Cyclooxygenase-2 inhibitor compositions having rapid onset of therapeutic effect
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United States of America Patent
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Feb 6, 2007
Grant Date -
Dec 30, 2004
app pub date -
Dec 6, 2000
filing date -
Dec 8, 1999
priority date (Note) -
Expired
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Abstract
Pharmaceutical compositions are provided comprising one or more orally deliverable dose units, each comprising a selective cyclooxygenase-2 inhibitory drug of low water solubility in a therapeutically effective amount, wherein the drug is present in the form of solid particle, about 25% to 100% by weight of which are smaller than 1 .mu.m. The compositions are useful in treatment or prophylaxis of cyclooxygenase-2 mediated conditions and disorders and have particular advantages where rapid onset of therapeutic effect is desired.
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