Promoter for smooth muscle cell expression

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United States of America Patent

PATENT NO 7169764
SERIAL NO

09381750

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Abstract

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Disclosed is a smooth muscle cell specific promoter, the SM22.alpha. gene promoter as well as the murine cDNA and genomic SM22.alpha. nucleic acid sequences. Also disclosed are methods of preventing restenosis following balloon angioplasty and methods of treating asthma based on inhibition of smooth muscle cell proliferation by expressing cell cycle control genes, or contraction inhibiting peptides in smooth muscle cells, under the control of the SM22.alpha. promoter.

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Patent Owner(s)

Patent OwnerAddress
ARCH DEVELOPMENT CORPORATION5640 SOUTH ELLIS AVENUE CHICAGO IL 606037

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Parmacek, Michael S Bryn Mawr, PA 7 219
Solway, Julian Glencoe, IL 11 239

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