Azulene derivatives and salts thereof
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United States of America Patent
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Jan 30, 2007
Grant Date -
Jun 9, 2005
app pub date -
Aug 4, 2003
filing date -
Aug 5, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention provides an azulene derivative and a salt thereof, wherein an azulene ring is bonded to a benzene ring directly or via a lower alkylene which may be substituted with a halogen atom and the benzene ring is directly bonded to the glucose residue, and it is usable as a Na.sup.+-glucose cotransporter inhibitor, especially for a therapeutic and/or preventive agent for diabetes such as insulin-dependent diabetes (type 1 diabetes) and insulin-independent diabetes (type 2 diabetes), as well as diabetes-related diseases such as insulin-resistant diseases and obesity.
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