Method to identify regulators of cellular activation using Bcl10

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United States of America Patent

PATENT NO 7169570
APP PUB NO 20040265915A1
SERIAL NO

10795157

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed are methods for evaluating the activation of Bcl10 in a cell in response to a putative stimulus, as well as methods for evaluating or identifying a regulatory compound which regulates activation of Bcl10-mediated signal transduction. These methods utilize the discovery of the activation-dependent formation in a cell of Bcl10 aggregates in a cell.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL JEWISH MEDICAL AND RESEARCH CENTER1400 JACKSON STREET DENVER CO 80206

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kappler, John W Denver, CO 7 147
Marrack, Philippa Denver, CO 13 375
Schaefer, Brian C Columbia, MD 2 1

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