Noc2 knockout mouse
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United States of America Patent
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Jan 23, 2007
Grant Date -
Jan 26, 2006
app pub date -
Apr 1, 2005
filing date -
Apr 2, 2004
priority date (Note) -
Expired
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Abstract
Disclosed are a mouse homozygous or heterozygous for the defect of the Noc2 gene, and a tissue and a cell of the mouse. The Noc2 knockout mice, which exhibit stress-related insulin hyposecretion and accumulation of secretory granules of increased size and irregular shape in exocrine cells, provide a test system used in the development of therapeutic drugs for related disorders.
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