Mouse model of myxomatous valvular disease
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United States of America Patent
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Jan 23, 2007
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app pub date -
Feb 10, 2003
filing date -
Feb 10, 2003
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Abstract
An animal selected for lacking heparan sulfate 3-O-sulfotransferase-1 activity is provided. This animal exhibits characteristics associated with myxomatous valvular disease and is useful for identifying agents which prevent, delay or treat myxomatous valvular disease. Methods of diagnosing myxomatous valvular disease are also provided.
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