Cells for detection of influenza and parainfluenza viruses
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United States of America Patent
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Dec 19, 2006
Grant Date -
Jan 5, 2006
app pub date -
Sep 2, 2005
filing date -
Apr 17, 2003
priority date (Note) -
Expired
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Abstract
The invention provides cell lines which are useful for the rapid detection and production of influenza and parainfluenza viruses. In particular, the invention relates to transgenic mink lung cells which show increased sensitivity to infection by influenza A, influenza B, or parainfluenza 3 viruses, or which are capable of enhanced productivity of infectious virions. The invention is suitable for use in culturing clinical influenza and parainfluenza virus isolates and for the production of influenza and parainfluenza virus for vaccine formulations, as antigen preparations for diagnostic applications, and for screening antiviral drugs.
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