Candida kefyr cytosine deaminase

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United States of America Patent

PATENT NO 7141404
SERIAL NO

10744548

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Abstract

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A new cytosine deaminase gene and protein from Candida kefyr are provided. This protein has increased ability to convert the 5-fluorocytosine prodrug to its toxic form when compared against the E. coli enzyme.

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Patent Owner(s)

Patent OwnerAddress
ONYX PHARMACEUTICALS INCONE AMGEN CENTER DRIVE THOUSAND OAKS CA 91320-1799

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Delaney, Amy M Belleville, MI 3 0
Laquerre, Sylvie Exton, PA 45 146
Omer, Charles A Ann Arbor, MI 11 70
Shen, Yuqiao Richmond, CA 13 73

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