Amine derivative
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United States of America Patent
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Nov 7, 2006
Grant Date -
Dec 29, 2005
app pub date -
Sep 9, 2003
filing date -
Sep 11, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention relates to (1S)-1-isobutoxymethyl-3-methylbutylamine useful as an intermediate in the synthesis of sodium (2S,3S)-3-[[(1S)-1-isobutoxymethyl-3-methylbutyl]carbamoyl]oxirane-2-carb-oxylate and a process for production thereof. The process comprises reacting L-leucinol with a compound represented by the following formula in the presence of a base and reducing the obtained (1S)-1-(2-methyl-2-propenoxymethyl)-3-methylbutyl-amine: ##STR00001## [in which X is a leaving group].
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