Tricyclic compounds protein kinase inhibitors for enhancing the efficacy of anti-neoplastic agents and radiation therapy

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United States of America Patent

PATENT NO 7132533
SERIAL NO

11187089

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Protein kinase, such as CHK-1, inhibiting tricyclic compounds of the following formula (wherein R.sup.2, R.sup.3 and R.sup.4 are as defined in the specification) ##STR00001## pharmaceutical compositions containing effective amounts of said compounds or their salts are useful as a single agent or in combination with an anti-neoplastic agent or therapeutic radiation having an anti-neoplastic effect for treating diseases or conditions such as cancers.

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Patent Owner(s)

Patent OwnerAddress
AGOURON PHARMACEUTICALS INCLA JOLLA CA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Benedict, Suzanne Carlsbad, CA 5 49
Bennett, Michael San Diego, CA 40 1146
Ninkovic, Sacha Carlsbad, CA 29 228
Rui, Eugene San Diego, CA 3 28
Teng, Min San Diego, CA 114 3404
Wang, Fen San Diego, CA 14 189
Wang, Yong San Diego, CA 1107 9670
Zhu, Jinjiang San Diego, CA 4 48

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