Penicillanic acid derivative compounds and methods of making
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United States of America Patent
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Oct 24, 2006
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app pub date -
May 27, 2004
filing date -
Dec 29, 1997
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Abstract
Compounds of formula I: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and n have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting .beta.-lactamase enzymes, for enhancing the activity of .beta.-lactam antibiotics, and for treating .beta.-lactam resistant bacterial infections in a mammal. The invention also provides pharmaceutical compositions, processes for preparing compounds of formula I, and novel intermediates useful for the synthesis of compounds of formula I.
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