Malaria polypeptides
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United States of America Patent
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Oct 24, 2006
Grant Date -
N/A
app pub date -
Sep 18, 1998
filing date -
Sep 19, 1997
priority date (Note) -
Expired
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Abstract
The present invention relates to carbohydrates capable of acting as receptors for malaria antigens present on the surfaces of malaria infected erythrocytes. The receptors according to the invention comprises negatively charged glycosaminoglycan-like moities, preferably sulphated. The invention also relates to novel malaria polypeptides capable of acting as ligands in relation to the receptors according to the invention. The invention also encompasses the use thereof as medicaments, pharmaceutical compositions containing the same as well as antibodies directed against said new ligands.
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