Dab.sup.9 derivatives of lipopeptide antibiotics and methods of making and using the same
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United States of America Patent
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Oct 24, 2006
Grant Date -
Jul 15, 2004
app pub date -
Jan 2, 2003
filing date -
Jan 3, 2002
priority date (Note) -
Expired
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Abstract
The present invention provides Dab.sup.9 derivatives of amphomycin-type lipopeptide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing such compounds, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.
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