Apparatus and method for synthesizing combinatorial libraries
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United States of America Patent
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Oct 17, 2006
Grant Date -
Oct 23, 2003
app pub date -
Dec 11, 2002
filing date -
May 20, 1998
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Abstract
An apparatus and method for synthesizing a combinatorial library comprising a plurality of chemical compounds such that the chemical composition of each compound is easily tracked. The library compounds are synthesized on solid-phase supports, which are spatially arranged in frames during synthesis according to a predetermined protocol, such that each solid-phase support passes through a series of unique spatial 2D or 3D addresses by which the chemical composition of each compound may be determined at any point during synthesis. Solid-phase supports include hollow tubular-shaped lanterns and gears.
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