RelA-associated inhibitor, process for producing the same and utilization thereof
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United States of America Patent
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Oct 10, 2006
Grant Date -
Aug 7, 2003
app pub date -
Feb 27, 2003
filing date -
Dec 3, 1998
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Human RelA-associated inhibitor (RAI) comprises 351 amino acids and is capable of binding to p65, a subunit of the transcription factor NF.kappa.B. A process for producing RAI, a cDNA encoding it, a fragment capable of hybridizing selectively to the cDNA sequence, a plasmid for expression and duplication comprising the cDNA, a host cell transformed with the plasmid, an antibody against the polypeptide, a pharmaceutical composition comprising the polypeptide or the antibody against it and a method for diagnosis of diseases using the antibody against the RAI are disclosed.
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