Quinoline derivative as diagnostic probe for disease with tau protein accumulation
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United States of America Patent
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Oct 10, 2006
Grant Date -
Jan 13, 2005
app pub date -
Nov 28, 2003
filing date -
Dec 16, 2002
priority date (Note) -
Expired
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Abstract
The present invention provides compounds, or salts or solvates thereof, which can be used as probes for the imaging diagnosis of diseases in which tau protein accumulates, and compositions and kits comprising such compounds, or salts or solvates thereof. The present invention also provides a method for staining neurofibrillary tangles in brain samples, and a pharmaceutical composition for the treatment and/or prophylaxis of a disease in which .beta.-sheet structure is the cause or possible cause.
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