Humanized antibody specific for surface antigen pre-S1 of HBV and preparation method thereof
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United States of America Patent
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Oct 3, 2006
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app pub date -
Nov 19, 1999
filing date -
Nov 19, 1998
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Abstract
The present invention relates to humanized antibodies specific for HBV surface antigen pre-S1, which show binding affinity similar to mouse monoclonal antibody and which show remarkably reduced immunogenicity since they have less mouse-derived amino acid residues. Thus, the humanized antibodies of the present invention may be useful for the prevention of HBV infection and for the treatment of hepatitis B.
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