Heterocyclic hydrazones for use as anti-cancer agents
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United States of America Patent
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Sep 26, 2006
Grant Date -
Sep 4, 2003
app pub date -
Jun 5, 2001
filing date -
Jun 5, 2000
priority date (Note) -
Expired
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Abstract
The invention relates to novel 2-benzimidazolyl-, 2-benzoxazolyl- and 2-benzothiazolyl hydrazones that are derived from 2-formylpyridine, 2-acylpyridines, acetyldiazines and acetyl(iso)quinolines. The invention also relates to a novel method for producing 2-benzimidazolyl-, 2-benzoxazolyl- and 2-benzothiazolyl hydrazones and to their use as useful anti-cancer therapeutic agents. The novel compounds are also active against multidrug-resistant cancer cells.
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