Pyrazole derivatives
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United States of America Patent
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Sep 19, 2006
Grant Date -
May 29, 2003
app pub date -
Apr 5, 2002
filing date -
Apr 10, 2001
priority date (Note) -
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Abstract
This invention relates to pyrazole derivatives of formula (I) ##STR00001## or pharmaceutically acceptable salts, solvates or derivatives thereof, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. As such, the compounds of the present invention are useful in the treatment of a variety of disorders including those in which the inhibition of reverse transcriptase is implicated. Disorders of interest include those caused by Human Immunodificiency Virus (HIV) and genetically related retroviruses, such as Acquired Immune Deficiency Syndrome (AIDS).
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