Immunogenicity using a combination of DNA and vaccinia virus vector vaccines
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United States of America Patent
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Aug 22, 2006
Grant Date -
Feb 19, 2004
app pub date -
Apr 30, 2001
filing date -
Apr 28, 2000
priority date (Note) -
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Abstract
This invention relates to improved methods of inducing an immune response for the prevention or treatment of HIV-1 infection by using a nucleic acid vaccine in conjunction with a recombinant viral vaccine, e.g., a poxvirus vaccine, to potentiate and broaden the immune response. The present invention further provides a particularly effective vaccine regimen comprising a DNA vaccine used in combination with a poxvirus virus, especially NYVAC or ALVAC.
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