Human VNO cDNA libraries
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United States of America Patent
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Aug 8, 2006
Grant Date -
Dec 4, 2003
app pub date -
Jun 12, 2003
filing date -
Feb 17, 2000
priority date (Note) -
Expired
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Abstract
This invention relates to DNA libraries, in particular a human VNO cDNA library is described. Pheromone receptor cDNA once isolated is transfected into competent cells. The transfected cell lines provide a scaleable source of homogeneous material to develop efficient, automated high throughput screening assays for new vomeropherins, and thereby reduce the ongoing need for human volunteers in the preclinical phases of drug discovery. Identification and characterization of the human VNO receptor(s) will facilitate the development and commercialization of vomeropherins with improved specificity, and enhanced therapeutic efficacy in the treatment of the target diseases.
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