Tyrosine recombinase for genetic engineering

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United States of America Patent

PATENT NO 7083976
APP PUB NO 20030113837A1
SERIAL NO

09895435

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Abstract

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The present invention is directed to methods and compositions for TnpI-mediated genetic engineering using the Bacillus thuringiensis recombinase TnpI and the TnpI recombination substrates TRT or TRT', and variants thereof. In particular, the invention relates to TRT or TRT' sequences, and variants thereof, vectors, cells and kits useful for TnpI-mediated genetic recombination, as well as methods for the use of TRT or TRT' sequences for TnpI-mediated genetic engineering.

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Patent Owner(s)

Patent OwnerAddress
EUROPEAN MOLECULAR BIOLOGY LABORATORY THEMEYERHOFSTRASSE 1 D-69117 HEIDELBERG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hallet, Bernard Sombreffe, BE 1 0
Stewart, A Francis Leimen, DE 2 54
Zhang, Youming Heidelberg, DE 34 177

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