Transgenic dunaliella salina as a bioreactor
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United States of America Patent
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Jul 25, 2006
Grant Date -
Apr 3, 2003
app pub date -
Nov 29, 2001
filing date -
Dec 3, 2000
priority date (Note) -
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Abstract
Disclosed is a method for making a bioreactor comprising a foreign target gene, special selectable markers and Dunaliella Salina as host. It is prepared by the genetic transformation techniques that include introducing a foreign target gene into the cells of Dunaliella Salina and screening the transformed cells of Dunaliella Salina. The bioreactor of the present invention can be used as a safe and cheap production system for proteins of pharmaceutical interest including vaccines, especially oral products, in a large scale, because the cells of Dunaliella Salina are easy of genetic manipulation in preparation of the bioreactor, nontoxic and edible for humans and animals, and harmless to the environment.
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