Pyrido[2,3-d]pyrimidine and pyrimido[4,5-d]pyrimidine nucleosides

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United States of America Patent

PATENT NO 7081449
APP PUB NO 20030144502A1
SERIAL NO

10221397

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Abstract

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A purine nucleoside analog includes a pyrido[2,3-d]pyrimidine or a pyrimido[4,5-d]pyrimidine and further has a sugar moiety that is optionally modified at the C2', C3', C4' and/or C5' position. Particularly contemplated compounds also include prodrug forms of the purine nucleoside analogs, and both purine nucleoside analogs and the corresponding prodrugs are employed in the reduction of growth of neoplastic cells.

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Patent Owner(s)

Patent OwnerAddress
MDRNA INC3830 MONTE VILLA PARKWAY BOTHELL WA 98021

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Girardet, Jean-Luc Aliso Viejo, CA 57 810
Gunic, Esmir Irvine, CA 38 506
Hong, Zhi Aliso Viejo, CA 70 1236
Lau, Johnson Newport Beach, CA 21 777
Pietrzkowski, Zbigniew San Diego, CA 41 345
Wang, Guangyi Carlsbad, CA 90 3414

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