Method for increasing HDL cholesterol level

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United States of America Patent

PATENT NO 7074407
SERIAL NO

09523033

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Abstract

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The present invention provides a method for increasing HDL cholesterol in a mammal by stimulating an immune response that inhibits the function of CETP. Such an immune response can be induced by immunizing with CETP or fragments of CETP (together termed 'CETP Peptides') which contain an epitope capable of stimulating such a response. The peptides can be conjugated to a carrier, such as KLH or ovalbumin, in order to increase immunogenicity. Adjuvants can also be administered.

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Patent Owner(s)

Patent OwnerAddress
CELLDEX THERAPEUTICS INC119 FOURTH AVENUE NEEDHAM MA 02494-2725

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brostoff, Steven W Carlsbad, CA 12 128
Carlo, Dennis J Rancho Santa Fe, CA 50 555
Kwoh, Deborah J Carlsbad, CA 1 1

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