Retroviral vectors with foreign-sequence insertion between retroviral primer binding site and retroviral splice donor
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United States of America Patent
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Jul 4, 2006
Grant Date -
Oct 31, 2002
app pub date -
Sep 10, 2001
filing date -
Sep 12, 2000
priority date (Note) -
Expired
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Abstract
The subject of the invention is retroviral gene transfer vectors in which foreign sequences are introduced between the retroviral primer binding site (PBS) and the retroviral splice donor (SD). The efficiency of gene expression is improved by this modification, and the vectors are characterized by an increased reliability during use.
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