Glycosyl sulfotransferases GST-4.alpha., GST-4.beta., and GST-6
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United States of America Patent
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Jul 4, 2006
Grant Date -
Sep 23, 2004
app pub date -
Oct 29, 2003
filing date -
Jul 20, 1999
priority date (Note) -
Expired
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Abstract
Novel glycosylsulfotransferases (GST-4.alpha., GST-4.beta., and GST-6) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including various diagnostic and therapeutic agent screening applications. Also provided are methods of inhibiting selectin mediated binding events and methods of treating disease conditions associated therewith, particularly by administering an inhibitor of at least one of GST-4.alpha., GST-4.beta., and GST-6.
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