Pharmaceutical compositions for lipophilic drugs
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United States of America Patent
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Jul 4, 2006
Grant Date -
N/A
app pub date -
Mar 5, 2001
filing date -
Jan 22, 1996
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Stable solutions of lipophilic drugs, such as cyclosporin, forming a polar lipid self-emulsifying drug delivery system. The solutions can include lipophilic drugs, such as cyclosporin, dissolved in a polar lipid, such as having a C.sub.6-C.sub.12 fatty acid monoglyceride content of at least about 50%, surfactants and triglycerides. The composition forms a fine emulsion on exposure to water. The encapsulated dosage form of this composition needs neither a hydrophilic component nor air-tight blister packaging, and is particularly suitable for oral administration.
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