Sodium ion-driven chloride/bi-carbonate exchanger
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United States of America Patent
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Jun 27, 2006
Grant Date -
Apr 1, 2004
app pub date -
Aug 14, 2003
filing date -
Aug 9, 2000
priority date (Note) -
Expired
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Abstract
The present invention discloses DNAs comprising nucleotide sequences set forth as SEQ ID NO:1 or NO:3 encoding Na.sup.+-driven Cl.sup.-/HCO.sub.3.sup.- exchanger, proteins comprising amino acid sequences set forth as SEQ ID NO:2 or NO:4, and their homologous proteins comprising an amino acid sequence having deletion, substitution, addition or insertion amino acids, which proteins, when expressed in a cell, functions as Na.sup.+-driven Cl.sup.-/HCO.sub.3.sup.- exchanger, and cells in which the proteins exogenously expressed.
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